PROSTAGLANDINS
- Latanoprost ( 0.005% )
- Bimatoprost ( 0.03% )
- Travopost (0.04% )
Mechanism Of Action :
Stimulation of FP class of prostaglandin receptors in ciliary body & iris root
↓
Increase in activity of matrix metalloproteinase enzyme
↓
Remodeling of extra cellular matrix & widening of intermuscular spaces in the ciliary body
↓
Increase in uveo sclera outflow
↓
Reduce IOP
Duration of Action : 24 hours
Frequency : OD
SIDE EFFECTS :
- Conjunctival hyperemia
- Trichomegaly / hypertrichosis : increased eye lashes
- Increased iris pigmentation
- Foreign body sensation