Prostaglandins

PROSTAGLANDINS

  1. Latanoprost ( 0.005% )
  2. Bimatoprost ( 0.03% )
  3. Travopost (0.04% )

Mechanism Of Action :

Stimulation of FP class of prostaglandin receptors in ciliary body & iris root

Increase in activity of matrix metalloproteinase enzyme

Remodeling of extra cellular matrix & widening of intermuscular spaces in the ciliary body

Increase in uveo sclera outflow

Reduce IOP

Duration of Action : 24 hours

Frequency : OD

SIDE EFFECTS :

  1. Conjunctival hyperemia
  2. Trichomegaly / hypertrichosis : increased eye lashes
  3. Increased iris pigmentation
  4. Foreign body sensation