MIOTICS (PARA SYMPATHOMIMETICS):
- Pilocarpine (2% & 4%)
- Carbachol
- Physiotigmine
- Disopropyl Flourophosphate
Mechanism Of Action:
- In Primary Open Angle Glaucoma,
contraction of longitudinal fibres of ciliary muscles
↓
pressure exerted on sclera spur
↓
change in trabecular meshwork
↓
increased aqueous outflow
↓
reduced IOP
- In Primary Angle Closure Glaucoma,
Mechanical contraction of pupil
↓
Moves iris away from trabecular meshwork
↓
Opening of the angle
↓
Increased outflow
↓
Reduced IOP.
